SNAPC1





























































小核RNA激活蛋白复合体,多肽1,43千道尔顿
Small nuclear RNA activating complex, polypeptide 1, 43kDa
标识
代号
SNAPC1; PTFgamma; SNAP43
扩展标识
遗传学:600591 鼠基因:1922877 同源基因:2317 GeneCards: SNAPC1 Gene



















RNA表达模式

PBB GE SNAPC1 205443 at tn.png

更多表达数据
直系同源体
物种
人类

小鼠
Entrez
6617

75627
Ensembl
ENSG00000023608

ENSMUSG00000021113
UniProt
Q16533

Q8K0S9
mRNA序列
NM_003082

NM_178392
蛋白序列
NP_003073

NP_848479
基因位置
Chr 14:
62.23 – 62.26 Mb


Chr 12:
73.96 – 73.98 Mb


PubMed查询

[1]

[2]

snRNA激活蛋白复合体第一亚基英语:snRNA-activating protein complex subunit 1)是一个由人类基因SNAPC1编码的蛋白质[1][2]



相互作用


SNAPC1能与SNAPC4[3]、SNAPC3[3][4]和视网膜母细胞瘤蛋白[5]发生相互作用。



参考文献





  1. ^ Maeng JH, Yoon JB. The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR. J Biochem. September 1998, 124 (1): 23–7. PMID 9644240. 


  2. ^ Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa. 


  3. ^ 3.03.1 Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.  引文使用过时参数coauthors (帮助)


  4. ^ Henry, R W; Ma B, Sadowski C L, Kobayashi R, Hernandez N. Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc. EMBO J. (ENGLAND). Dec 1996, 15 (24): 7129–36. ISSN 0261-4189. PMC 452539. PMID 9003788.  引文使用过时参数coauthors (帮助)


  5. ^ Hirsch, H A; Gu L, Henry R W. The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression. Mol. Cell. Biol. (UNITED STATES). Dec 2000, 20 (24): 9182–91. ISSN 0270-7306. PMC 102176. PMID 11094070. doi:10.1128/MCB.20.24.9182-9191.2000.  引文使用过时参数coauthors (帮助)




延伸阅读


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  • Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995, 374 (6523): 653–6. PMID 7715707. doi:10.1038/374653a0. 


  • Yoon JB, Roeder RG. Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein. Mol. Cell. Biol. Advances in Molecular and Cell Biology. 1996, 16 (1): 1–9. ISBN 978-0-7623-0143-0. PMC 230972. PMID 8524284. doi:10.1016/S1569-2558(08)60061-2. 


  • Henry RW, Ma B, Sadowski CL; 等. Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc. EMBO J. 1997, 15 (24): 7129–36. PMC 452539. PMID 9003788.  引文格式1维护:显式使用等标签 (link)


  • Ma B, Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. 2001, 276 (7): 5027–35. PMID 11056176. doi:10.1074/jbc.M009301200. 


  • Hirsch HA, Gu L, Henry RW. The Retinoblastoma Tumor Suppressor Protein Targets Distinct General Transcription Factors To Regulate RNA Polymerase III Gene Expression. Mol. Cell. Biol. 2001, 20 (24): 9182–91. PMC 102176. PMID 11094070. doi:10.1128/MCB.20.24.9182-9191.2000. 


  • Strausberg RL, Feingold EA, Grouse LH; 等. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899.  引文格式1维护:显式使用等标签 (link)


  • Hinkley CS, Hirsch HA, Gu L; 等. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. J. Biol. Chem. 2003, 278 (20): 18649–57. PMID 12621023. doi:10.1074/jbc.M204247200.  引文格式1维护:显式使用等标签 (link)


  • Gerhard DS, Wagner L, Feingold EA; 等. The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC). Genome Res. 2004, 14 (10B): 2121–7. PMC 528928. PMID 15489334. doi:10.1101/gr.2596504.  引文格式1维护:显式使用等标签 (link)


  • Gu L, Esselman WJ, Henry RW. Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC. J. Biol. Chem. 2005, 280 (30): 27697–704. PMID 15955816. doi:10.1074/jbc.M503206200. 


  • Rual JF, Venkatesan K, Hao T; 等. Towards a proteome-scale map of the human protein-protein interaction network. Nature. 2005, 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.  引文格式1维护:显式使用等标签 (link)












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