Need a suitable toxic chemical for a murder plot in my novel












8












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I need ideas for a chemical or disease which kills the victim upon holding it in the palm for about 4 or 5 seconds. The death isn't necessarily immediate, as it might take days to kill the victim in the case of an incurable disease.



If the substance can't kill the victim, at least it should cause permanent damage to the heart, nervous system, or brain. An overall skin disfigurement or damage to any other vital organs will be okay!



Something mixed in DMSO?



The specific chemical or disease should be somewhat easy to acquire with some effort for a common man because it must sound obvious for the readers.



Don't suggest nerve agents or Anthrax please. Because they are inaccessible for a common man.










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  • 13




    $begingroup$
    I think anything that can kill by 5-seconds contact with bare skin is inacessible to common people.
    $endgroup$
    – Renan
    yesterday








  • 26




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    When questions like this are posted I always worry someone is trying to kill someone in real life.
    $endgroup$
    – Willk
    yesterday






  • 2




    $begingroup$
    Welcome to Worldbuilding.SE! We're glad you could join us! When you have a moment, please click here to learn more about our culture and take our tour. I'm not sure why people are voting to close your question (real-world questions are permitted and this is an application of tech, which is one of our strengths). However, you might be asking for something that doesn't exist. A toxin that kills by limited touch but is accessible to common people is unbelievable. Such a toxin would be a controlled substance.
    $endgroup$
    – JBH
    yesterday






  • 2




    $begingroup$
    First, we'd have to know how you plan to get it to your victim without killing yourself in the process.
    $endgroup$
    – jamesqf
    yesterday






  • 4




    $begingroup$
    Presumably everybody in the world could kill anyone at any time, at what age are children given access to this household asassination weapon?
    $endgroup$
    – Agrajag
    yesterday
















8












$begingroup$


I need ideas for a chemical or disease which kills the victim upon holding it in the palm for about 4 or 5 seconds. The death isn't necessarily immediate, as it might take days to kill the victim in the case of an incurable disease.



If the substance can't kill the victim, at least it should cause permanent damage to the heart, nervous system, or brain. An overall skin disfigurement or damage to any other vital organs will be okay!



Something mixed in DMSO?



The specific chemical or disease should be somewhat easy to acquire with some effort for a common man because it must sound obvious for the readers.



Don't suggest nerve agents or Anthrax please. Because they are inaccessible for a common man.










share|improve this question









New contributor




user63214 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
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$endgroup$








  • 13




    $begingroup$
    I think anything that can kill by 5-seconds contact with bare skin is inacessible to common people.
    $endgroup$
    – Renan
    yesterday








  • 26




    $begingroup$
    When questions like this are posted I always worry someone is trying to kill someone in real life.
    $endgroup$
    – Willk
    yesterday






  • 2




    $begingroup$
    Welcome to Worldbuilding.SE! We're glad you could join us! When you have a moment, please click here to learn more about our culture and take our tour. I'm not sure why people are voting to close your question (real-world questions are permitted and this is an application of tech, which is one of our strengths). However, you might be asking for something that doesn't exist. A toxin that kills by limited touch but is accessible to common people is unbelievable. Such a toxin would be a controlled substance.
    $endgroup$
    – JBH
    yesterday






  • 2




    $begingroup$
    First, we'd have to know how you plan to get it to your victim without killing yourself in the process.
    $endgroup$
    – jamesqf
    yesterday






  • 4




    $begingroup$
    Presumably everybody in the world could kill anyone at any time, at what age are children given access to this household asassination weapon?
    $endgroup$
    – Agrajag
    yesterday














8












8








8


1



$begingroup$


I need ideas for a chemical or disease which kills the victim upon holding it in the palm for about 4 or 5 seconds. The death isn't necessarily immediate, as it might take days to kill the victim in the case of an incurable disease.



If the substance can't kill the victim, at least it should cause permanent damage to the heart, nervous system, or brain. An overall skin disfigurement or damage to any other vital organs will be okay!



Something mixed in DMSO?



The specific chemical or disease should be somewhat easy to acquire with some effort for a common man because it must sound obvious for the readers.



Don't suggest nerve agents or Anthrax please. Because they are inaccessible for a common man.










share|improve this question









New contributor




user63214 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
Check out our Code of Conduct.







$endgroup$




I need ideas for a chemical or disease which kills the victim upon holding it in the palm for about 4 or 5 seconds. The death isn't necessarily immediate, as it might take days to kill the victim in the case of an incurable disease.



If the substance can't kill the victim, at least it should cause permanent damage to the heart, nervous system, or brain. An overall skin disfigurement or damage to any other vital organs will be okay!



Something mixed in DMSO?



The specific chemical or disease should be somewhat easy to acquire with some effort for a common man because it must sound obvious for the readers.



Don't suggest nerve agents or Anthrax please. Because they are inaccessible for a common man.







science-fiction chemistry biochemistry medicine poisons






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edited yesterday









Cyn

11.7k12458




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asked yesterday









user63214user63214

473




473




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user63214 is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
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  • 13




    $begingroup$
    I think anything that can kill by 5-seconds contact with bare skin is inacessible to common people.
    $endgroup$
    – Renan
    yesterday








  • 26




    $begingroup$
    When questions like this are posted I always worry someone is trying to kill someone in real life.
    $endgroup$
    – Willk
    yesterday






  • 2




    $begingroup$
    Welcome to Worldbuilding.SE! We're glad you could join us! When you have a moment, please click here to learn more about our culture and take our tour. I'm not sure why people are voting to close your question (real-world questions are permitted and this is an application of tech, which is one of our strengths). However, you might be asking for something that doesn't exist. A toxin that kills by limited touch but is accessible to common people is unbelievable. Such a toxin would be a controlled substance.
    $endgroup$
    – JBH
    yesterday






  • 2




    $begingroup$
    First, we'd have to know how you plan to get it to your victim without killing yourself in the process.
    $endgroup$
    – jamesqf
    yesterday






  • 4




    $begingroup$
    Presumably everybody in the world could kill anyone at any time, at what age are children given access to this household asassination weapon?
    $endgroup$
    – Agrajag
    yesterday














  • 13




    $begingroup$
    I think anything that can kill by 5-seconds contact with bare skin is inacessible to common people.
    $endgroup$
    – Renan
    yesterday








  • 26




    $begingroup$
    When questions like this are posted I always worry someone is trying to kill someone in real life.
    $endgroup$
    – Willk
    yesterday






  • 2




    $begingroup$
    Welcome to Worldbuilding.SE! We're glad you could join us! When you have a moment, please click here to learn more about our culture and take our tour. I'm not sure why people are voting to close your question (real-world questions are permitted and this is an application of tech, which is one of our strengths). However, you might be asking for something that doesn't exist. A toxin that kills by limited touch but is accessible to common people is unbelievable. Such a toxin would be a controlled substance.
    $endgroup$
    – JBH
    yesterday






  • 2




    $begingroup$
    First, we'd have to know how you plan to get it to your victim without killing yourself in the process.
    $endgroup$
    – jamesqf
    yesterday






  • 4




    $begingroup$
    Presumably everybody in the world could kill anyone at any time, at what age are children given access to this household asassination weapon?
    $endgroup$
    – Agrajag
    yesterday








13




13




$begingroup$
I think anything that can kill by 5-seconds contact with bare skin is inacessible to common people.
$endgroup$
– Renan
yesterday






$begingroup$
I think anything that can kill by 5-seconds contact with bare skin is inacessible to common people.
$endgroup$
– Renan
yesterday






26




26




$begingroup$
When questions like this are posted I always worry someone is trying to kill someone in real life.
$endgroup$
– Willk
yesterday




$begingroup$
When questions like this are posted I always worry someone is trying to kill someone in real life.
$endgroup$
– Willk
yesterday




2




2




$begingroup$
Welcome to Worldbuilding.SE! We're glad you could join us! When you have a moment, please click here to learn more about our culture and take our tour. I'm not sure why people are voting to close your question (real-world questions are permitted and this is an application of tech, which is one of our strengths). However, you might be asking for something that doesn't exist. A toxin that kills by limited touch but is accessible to common people is unbelievable. Such a toxin would be a controlled substance.
$endgroup$
– JBH
yesterday




$begingroup$
Welcome to Worldbuilding.SE! We're glad you could join us! When you have a moment, please click here to learn more about our culture and take our tour. I'm not sure why people are voting to close your question (real-world questions are permitted and this is an application of tech, which is one of our strengths). However, you might be asking for something that doesn't exist. A toxin that kills by limited touch but is accessible to common people is unbelievable. Such a toxin would be a controlled substance.
$endgroup$
– JBH
yesterday




2




2




$begingroup$
First, we'd have to know how you plan to get it to your victim without killing yourself in the process.
$endgroup$
– jamesqf
yesterday




$begingroup$
First, we'd have to know how you plan to get it to your victim without killing yourself in the process.
$endgroup$
– jamesqf
yesterday




4




4




$begingroup$
Presumably everybody in the world could kill anyone at any time, at what age are children given access to this household asassination weapon?
$endgroup$
– Agrajag
yesterday




$begingroup$
Presumably everybody in the world could kill anyone at any time, at what age are children given access to this household asassination weapon?
$endgroup$
– Agrajag
yesterday










7 Answers
7






active

oldest

votes


















21












$begingroup$

The canonical example is



Dimethylmercury




Dimethylmercury is an organomercury compound. A highly volatile, reactive, flammable, and colorless liquid, dimethylmercury is one of the strongest known neurotoxins, with a quantity of less than 0.1 mL capable of inducing severe mercury poisoning, and is easily absorbed through the skin. Dimethylmercury is capable of permeating many materials, including plastic and rubber compounds. It has a slightly sweet odor, although inhaling enough of the chemical to notice this would be hazardous. (Wikipedia, s.v. dimethylmercury)



Dimethylmercury is extremely toxic and dangerous to handle. Absorption of doses as low as 0.1 mL can result in severe mercury poisoning. The risks are enhanced because of the high vapor pressure of the liquid.



Permeation tests showed that several types of disposable latex or polyvinyl chloride gloves (typically, about 0.1 mm thick), commonly used in most laboratories and clinical settings, had high and maximal rates of permeation by dimethylmercury within 15 seconds. The American Occupational Safety and Health Administration advises handling dimethylmercury with highly resistant laminated gloves with an additional pair of abrasion-resistant gloves worn over the laminate pair, and also recommends using a face shield and working in a fume hood.



Dimethylmercury is metabolized after several days to methylmercury. Methylmercury crosses the blood–brain barrier easily, probably owing to formation of a complex with cysteine. It is eliminated from the organism slowly, and therefore has a tendency to bioaccumulate. The symptoms of poisoning may be delayed by months, resulting in cases in which a diagnosis is ultimately discovered, but only at the point in which it is too late for an effective treatment regimen to be successful.



The toxicity of dimethylmercury was highlighted with the death of Karen Wetterhahn, a professor of chemistry at Dartmouth College, in 1997. Professor Wetterhahn specialized in heavy metal poisoning. After she spilled a few drops of this compound on her latex glove, the barrier was compromised, and within minutes it was absorbed into her skin. It circulated through her body and accumulated in her brain, resulting in her death ten months later. This accident is a common toxicology case-study and directly resulted in improved safety procedures for chemical-protection clothing and fume use, which are now called for when any exposure to such severely toxic and/or highly penetrative substances is possible (e.g., in chemical munitions stockpiles and decontamination facilities).




The beauty of it is that dimethylmercury is easily synthesized:




The compound was one of the earliest organometallics reported, reflecting its considerable stability. It is formed by treating sodium amalgam with methyl halides:



$mathrm{Hg} + 2 mathrm{Na} + 2 mathrm {CH}_3mathrm{I} rightarrow mathrm {Hg}(mathrm{CH}_3)_2 + 2 mathrm {NaI}$




Methyl iodide ($mathrm {CH}_3mathrm{I}$) itself is also easy to make.



All in all, all you need in order to make one the deadliest known substances is access to a high-school chemistry laboratory.






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  • $begingroup$
    Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
    $endgroup$
    – WhatRoughBeast
    yesterday






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    @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
    $endgroup$
    – Ville Niemi
    yesterday



















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Honeybee.



bee
https://cronkitenews.azpbs.org/2018/02/21/advocacy-groups-pressure-state-to-ban-bee-killing-pesticides/



I like this because if your victim is allergic, he can very definitely die from a bee sting. It takes seconds to get stung. This method is not applicable to the general population, so if user63214 is some disgruntled would-be murderer I am not an accessory. But for a story it could work just fine.






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  • 6




    $begingroup$
    I love the way your mind works.
    $endgroup$
    – JBH
    yesterday










  • $begingroup$
    Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
    $endgroup$
    – DarthDonut
    17 hours ago






  • 2




    $begingroup$
    @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
    $endgroup$
    – wizzwizz4
    16 hours ago





















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  • Caffeine


    • known to work with DMSO (some people consume it this way)

    • wikipedia: "pure powdered caffeine, which is available as a dietary supplement, can be lethal in tablespoon-sized amounts"



  • Warfarin


    • accessible as rat poison

    • a few grams should be enough (1-5 mg tablets are used in medicine)

    • use with DMSO? no idea if that would work

    • causes bleeding, necrosis...



  • Hydrofluoric acid


    • indirectly accessible in glass etching kits

    • or you can just buy it

    • how scary do you wish your novel to be?








share|improve this answer









$endgroup$









  • 1




    $begingroup$
    " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
    $endgroup$
    – FooBar
    15 hours ago



















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$begingroup$

Ricin



See here and here.



Made from the castor bean, the plant can be found as a common ornamental in parks and gardens.



There is no antidote.



@AlexP also provides a great vector.



I am not going in to production and delivery but no special requirements and a little creative thought should show how this could be achieved.






share|improve this answer









$endgroup$













  • $begingroup$
    The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
    $endgroup$
    – Stormbolter
    15 hours ago










  • $begingroup$
    Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
    $endgroup$
    – pHred
    4 hours ago



















1












$begingroup$

Here's another accessible chemical compound that hasn't been mentioned so far:



Dimethyl sulfate




Like all strong alkylating agents, $(text{CH}_3text{O})_2text{SO}_2$ or $text{Me}_2text{SO}_4$ is extremely toxic. Its use as a laboratory reagent has been superseded to some extent by methyl triflate, the methyl ester of trifluoromethanesulfonic acid.




It can be synthesized in the laboratory by many different methods, the simplest being the esterification of sulfuric acid with methanol. Another possible synthesis involves distillation of methyl hydrogen sulfate.




Dimethyl sulfate is carcinogenic and mutagenic, highly poisonous, corrosive, and environmentally hazardous. Dimethyl sulfate is absorbed through the skin, mucous membranes, and gastrointestinal tract, and can cause a fatal delayed respiratory tract reaction. An ocular reaction is also common. There is no strong odor or immediate irritation to warn of lethal concentration in the air.







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    0












    $begingroup$

    While i do not know of any easily obtained chemicals or substances that can kill as you just through contact of your palm (probably a good thing for the general population) i can offer you some ideas.



    Delivery



    Firstly though, i am going to present you with a possible delivery system. As many chemicals need to be in your bloodstream to take effect, we would need some way of transferring them there. Thusly, i present you with The Assassin’s Glove (name pending).



    This would be a glove who’s palm is laced with hypodermic needles, similar to those you may find in nettles. As you shook someone’s hand, these needles would be pressed against their palm and inject the substance into their body. With this glove, you could inject practically anything into the target. Here are some suggestions:



    Substances



    Snake venom is relatively easy to obtain, assuming you can find and extract the venom from one. However, as it is a venom, it can’t kill you unless it enters your blood stream. You can safely drink snake venom if you do not have any cuts from your mouth to your stomach. However, if you had a cut or it was injected into you, then you would feel its effects.



    Cyanide is a classic killer, you can extract it from apple seeds if your protagonist truly has no access to any kind of harmful substance.



    Hydrochloric acid, extracted from bleach, may also do the job. Bleach does have a strong smell to it though which may give your assassin away.



    Alternatively



    If you’re just looking for a way to stealthily kill someone, polonium has famously been used. It is a radioactive substance which emits alpha radiation. Alpha radiation can not penetrate human skin but, of ingested, it is fatal. The reason it kills you is the same reason you are normally safe from it, it can’t penetrate your skin, meaning its stuck inside you and damages your DNA. It would likely take weeks or months to kill someone this way but it has been used in the past. You might also be able to inject it to get a similar effect.






    share|improve this answer









    $endgroup$









    • 1




      $begingroup$
      Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
      $endgroup$
      – jwenting
      19 hours ago










    • $begingroup$
      Contaminating the toothbrush is way more creative than the assassin's glove.
      $endgroup$
      – polfosol
      16 hours ago



















    -1












    $begingroup$

    Elemental Mercury



    Okay, this doesn't really meet your requirements. Not much is absorbed through the skin. But mercury in your hand is fun to play with and your victim might keep it on longer than 4-5 seconds. The danger is from the vapors. If your plot allows, pouring large amounts of mercury around the victim's bed or car, or another relatively small space where the victim spends a lot of time, might do the trick.



    Elemental mercury is what's in thermometers (the kind without batteries), so it would be relatively simple (though expensive and time consuming) to gather enough for the perpetrator to use (assuming a lot of safety equipment, the kind easily found online). The more dangerous form of mercury is methyl mercury, but that's not exactly sold in handy dandy glass containers. Mercury also has medical applications but purchasing it in larger quantities might prove more difficult.



    Instead of buying old fashioned thermometers, the perp might want to buy new digital ones and offer them free to doctor's clinics and households and schools in exchange for mercury ones (as a way to reduce potential toxic exposures...swap programs like this probably already exist legitimately). You may also have some luck with fluorescent light bulbs.




    Elemental mercury, also called “quicksilver,” is a heavy, silvery,
    form of the metal mercury that is liquid at room temperature. It can
    slowly change from a liquid into a gas that is invisible to the naked
    eye. The gas or “vapors” that are released will start to fill a room
    if mercury is spilled indoors.



    Mercury is a very
    toxic or poisonous substance that people can be exposed to in several
    ways. If it is swallowed, like from a broken thermometer, it mostly
    passes through your body and very little is absorbed. If you touch it,
    a small amount may pass through your skin, but not usually enough to
    harm you. Mercury is most harmful when you breathe in the vapors that
    are released when a container is open or a spill occurs. (ref)




    Will elemental mercury fumes kill a victim? Maybe. But organ damage (which you allow as an alternative) is more likely.




    How much mercury spilled in a room will make air in the room unsafe?
    Any amount of mercury spilled indoors can be hazardous. The more
    mercury is spilled, the more its vapor will build up in air and the
    more hazardous it will be. Even a small spill, such as from a broken
    thermometer, can produce hazardous amounts of vapor if a room is small
    enough, warm enough and people spend a good deal of time there, as in
    a small bedroom.
    (ref)




    Spilling the mercury on to a hot surface (like a stove) will vaporize it quickly. Spilling it elsewhere will allow the vapors to accumulate more slowly. The liquid form is easily tracked through a house and hard to get rid of.




    Inhalation of elemental mercury vapors is the main source of toxicity,
    as mercury is well-absorbed through the lungs. Problems from
    inhalation result either from a large one-time high exposure or a
    long-term exposure. Long-term exposure of inhaled vapors is generally
    more dangerous, with the nervous system being the primary target of
    mercury toxicity. Symptoms may occur within weeks but usually develop
    insidiously over a period of years. Neurologic symptoms include
    tremors, headaches, short-term memory loss, incoordination, weakness,
    loss of appetite, altered sense of taste and smell, numbness and
    tingling in the hands and feet, insomnia, and excessive sweating.
    Psychiatric effects are also seen after long-term exposure. The
    kidneys can also be effected. Intense exposure to high concentrations
    of mercury vapor can lead to severe respiratory damage
    . (ref)




    So there you have it. Organ damage from even short-term exposures. But not from being held in the hand. Consider that a frame challenge, that the substance you are imagining probably does not exist. But you can combine mercury in the hand with mercury spilling all over the place and creating fumes. Maybe try when the victim is locked into a sauna for an hour. There are many possibilities.






    share|improve this answer











    $endgroup$









    • 3




      $begingroup$
      Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
      $endgroup$
      – AlexP
      yesterday












    • $begingroup$
      @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
      $endgroup$
      – Cyn
      yesterday










    • $begingroup$
      There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
      $endgroup$
      – Cyn
      yesterday










    • $begingroup$
      @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
      $endgroup$
      – jwenting
      19 hours ago










    • $begingroup$
      @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
      $endgroup$
      – Cyn
      16 hours ago












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    7 Answers
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    7 Answers
    7






    active

    oldest

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    active

    oldest

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    active

    oldest

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    21












    $begingroup$

    The canonical example is



    Dimethylmercury




    Dimethylmercury is an organomercury compound. A highly volatile, reactive, flammable, and colorless liquid, dimethylmercury is one of the strongest known neurotoxins, with a quantity of less than 0.1 mL capable of inducing severe mercury poisoning, and is easily absorbed through the skin. Dimethylmercury is capable of permeating many materials, including plastic and rubber compounds. It has a slightly sweet odor, although inhaling enough of the chemical to notice this would be hazardous. (Wikipedia, s.v. dimethylmercury)



    Dimethylmercury is extremely toxic and dangerous to handle. Absorption of doses as low as 0.1 mL can result in severe mercury poisoning. The risks are enhanced because of the high vapor pressure of the liquid.



    Permeation tests showed that several types of disposable latex or polyvinyl chloride gloves (typically, about 0.1 mm thick), commonly used in most laboratories and clinical settings, had high and maximal rates of permeation by dimethylmercury within 15 seconds. The American Occupational Safety and Health Administration advises handling dimethylmercury with highly resistant laminated gloves with an additional pair of abrasion-resistant gloves worn over the laminate pair, and also recommends using a face shield and working in a fume hood.



    Dimethylmercury is metabolized after several days to methylmercury. Methylmercury crosses the blood–brain barrier easily, probably owing to formation of a complex with cysteine. It is eliminated from the organism slowly, and therefore has a tendency to bioaccumulate. The symptoms of poisoning may be delayed by months, resulting in cases in which a diagnosis is ultimately discovered, but only at the point in which it is too late for an effective treatment regimen to be successful.



    The toxicity of dimethylmercury was highlighted with the death of Karen Wetterhahn, a professor of chemistry at Dartmouth College, in 1997. Professor Wetterhahn specialized in heavy metal poisoning. After she spilled a few drops of this compound on her latex glove, the barrier was compromised, and within minutes it was absorbed into her skin. It circulated through her body and accumulated in her brain, resulting in her death ten months later. This accident is a common toxicology case-study and directly resulted in improved safety procedures for chemical-protection clothing and fume use, which are now called for when any exposure to such severely toxic and/or highly penetrative substances is possible (e.g., in chemical munitions stockpiles and decontamination facilities).




    The beauty of it is that dimethylmercury is easily synthesized:




    The compound was one of the earliest organometallics reported, reflecting its considerable stability. It is formed by treating sodium amalgam with methyl halides:



    $mathrm{Hg} + 2 mathrm{Na} + 2 mathrm {CH}_3mathrm{I} rightarrow mathrm {Hg}(mathrm{CH}_3)_2 + 2 mathrm {NaI}$




    Methyl iodide ($mathrm {CH}_3mathrm{I}$) itself is also easy to make.



    All in all, all you need in order to make one the deadliest known substances is access to a high-school chemistry laboratory.






    share|improve this answer











    $endgroup$













    • $begingroup$
      Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
      $endgroup$
      – WhatRoughBeast
      yesterday






    • 2




      $begingroup$
      @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
      $endgroup$
      – Ville Niemi
      yesterday
















    21












    $begingroup$

    The canonical example is



    Dimethylmercury




    Dimethylmercury is an organomercury compound. A highly volatile, reactive, flammable, and colorless liquid, dimethylmercury is one of the strongest known neurotoxins, with a quantity of less than 0.1 mL capable of inducing severe mercury poisoning, and is easily absorbed through the skin. Dimethylmercury is capable of permeating many materials, including plastic and rubber compounds. It has a slightly sweet odor, although inhaling enough of the chemical to notice this would be hazardous. (Wikipedia, s.v. dimethylmercury)



    Dimethylmercury is extremely toxic and dangerous to handle. Absorption of doses as low as 0.1 mL can result in severe mercury poisoning. The risks are enhanced because of the high vapor pressure of the liquid.



    Permeation tests showed that several types of disposable latex or polyvinyl chloride gloves (typically, about 0.1 mm thick), commonly used in most laboratories and clinical settings, had high and maximal rates of permeation by dimethylmercury within 15 seconds. The American Occupational Safety and Health Administration advises handling dimethylmercury with highly resistant laminated gloves with an additional pair of abrasion-resistant gloves worn over the laminate pair, and also recommends using a face shield and working in a fume hood.



    Dimethylmercury is metabolized after several days to methylmercury. Methylmercury crosses the blood–brain barrier easily, probably owing to formation of a complex with cysteine. It is eliminated from the organism slowly, and therefore has a tendency to bioaccumulate. The symptoms of poisoning may be delayed by months, resulting in cases in which a diagnosis is ultimately discovered, but only at the point in which it is too late for an effective treatment regimen to be successful.



    The toxicity of dimethylmercury was highlighted with the death of Karen Wetterhahn, a professor of chemistry at Dartmouth College, in 1997. Professor Wetterhahn specialized in heavy metal poisoning. After she spilled a few drops of this compound on her latex glove, the barrier was compromised, and within minutes it was absorbed into her skin. It circulated through her body and accumulated in her brain, resulting in her death ten months later. This accident is a common toxicology case-study and directly resulted in improved safety procedures for chemical-protection clothing and fume use, which are now called for when any exposure to such severely toxic and/or highly penetrative substances is possible (e.g., in chemical munitions stockpiles and decontamination facilities).




    The beauty of it is that dimethylmercury is easily synthesized:




    The compound was one of the earliest organometallics reported, reflecting its considerable stability. It is formed by treating sodium amalgam with methyl halides:



    $mathrm{Hg} + 2 mathrm{Na} + 2 mathrm {CH}_3mathrm{I} rightarrow mathrm {Hg}(mathrm{CH}_3)_2 + 2 mathrm {NaI}$




    Methyl iodide ($mathrm {CH}_3mathrm{I}$) itself is also easy to make.



    All in all, all you need in order to make one the deadliest known substances is access to a high-school chemistry laboratory.






    share|improve this answer











    $endgroup$













    • $begingroup$
      Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
      $endgroup$
      – WhatRoughBeast
      yesterday






    • 2




      $begingroup$
      @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
      $endgroup$
      – Ville Niemi
      yesterday














    21












    21








    21





    $begingroup$

    The canonical example is



    Dimethylmercury




    Dimethylmercury is an organomercury compound. A highly volatile, reactive, flammable, and colorless liquid, dimethylmercury is one of the strongest known neurotoxins, with a quantity of less than 0.1 mL capable of inducing severe mercury poisoning, and is easily absorbed through the skin. Dimethylmercury is capable of permeating many materials, including plastic and rubber compounds. It has a slightly sweet odor, although inhaling enough of the chemical to notice this would be hazardous. (Wikipedia, s.v. dimethylmercury)



    Dimethylmercury is extremely toxic and dangerous to handle. Absorption of doses as low as 0.1 mL can result in severe mercury poisoning. The risks are enhanced because of the high vapor pressure of the liquid.



    Permeation tests showed that several types of disposable latex or polyvinyl chloride gloves (typically, about 0.1 mm thick), commonly used in most laboratories and clinical settings, had high and maximal rates of permeation by dimethylmercury within 15 seconds. The American Occupational Safety and Health Administration advises handling dimethylmercury with highly resistant laminated gloves with an additional pair of abrasion-resistant gloves worn over the laminate pair, and also recommends using a face shield and working in a fume hood.



    Dimethylmercury is metabolized after several days to methylmercury. Methylmercury crosses the blood–brain barrier easily, probably owing to formation of a complex with cysteine. It is eliminated from the organism slowly, and therefore has a tendency to bioaccumulate. The symptoms of poisoning may be delayed by months, resulting in cases in which a diagnosis is ultimately discovered, but only at the point in which it is too late for an effective treatment regimen to be successful.



    The toxicity of dimethylmercury was highlighted with the death of Karen Wetterhahn, a professor of chemistry at Dartmouth College, in 1997. Professor Wetterhahn specialized in heavy metal poisoning. After she spilled a few drops of this compound on her latex glove, the barrier was compromised, and within minutes it was absorbed into her skin. It circulated through her body and accumulated in her brain, resulting in her death ten months later. This accident is a common toxicology case-study and directly resulted in improved safety procedures for chemical-protection clothing and fume use, which are now called for when any exposure to such severely toxic and/or highly penetrative substances is possible (e.g., in chemical munitions stockpiles and decontamination facilities).




    The beauty of it is that dimethylmercury is easily synthesized:




    The compound was one of the earliest organometallics reported, reflecting its considerable stability. It is formed by treating sodium amalgam with methyl halides:



    $mathrm{Hg} + 2 mathrm{Na} + 2 mathrm {CH}_3mathrm{I} rightarrow mathrm {Hg}(mathrm{CH}_3)_2 + 2 mathrm {NaI}$




    Methyl iodide ($mathrm {CH}_3mathrm{I}$) itself is also easy to make.



    All in all, all you need in order to make one the deadliest known substances is access to a high-school chemistry laboratory.






    share|improve this answer











    $endgroup$



    The canonical example is



    Dimethylmercury




    Dimethylmercury is an organomercury compound. A highly volatile, reactive, flammable, and colorless liquid, dimethylmercury is one of the strongest known neurotoxins, with a quantity of less than 0.1 mL capable of inducing severe mercury poisoning, and is easily absorbed through the skin. Dimethylmercury is capable of permeating many materials, including plastic and rubber compounds. It has a slightly sweet odor, although inhaling enough of the chemical to notice this would be hazardous. (Wikipedia, s.v. dimethylmercury)



    Dimethylmercury is extremely toxic and dangerous to handle. Absorption of doses as low as 0.1 mL can result in severe mercury poisoning. The risks are enhanced because of the high vapor pressure of the liquid.



    Permeation tests showed that several types of disposable latex or polyvinyl chloride gloves (typically, about 0.1 mm thick), commonly used in most laboratories and clinical settings, had high and maximal rates of permeation by dimethylmercury within 15 seconds. The American Occupational Safety and Health Administration advises handling dimethylmercury with highly resistant laminated gloves with an additional pair of abrasion-resistant gloves worn over the laminate pair, and also recommends using a face shield and working in a fume hood.



    Dimethylmercury is metabolized after several days to methylmercury. Methylmercury crosses the blood–brain barrier easily, probably owing to formation of a complex with cysteine. It is eliminated from the organism slowly, and therefore has a tendency to bioaccumulate. The symptoms of poisoning may be delayed by months, resulting in cases in which a diagnosis is ultimately discovered, but only at the point in which it is too late for an effective treatment regimen to be successful.



    The toxicity of dimethylmercury was highlighted with the death of Karen Wetterhahn, a professor of chemistry at Dartmouth College, in 1997. Professor Wetterhahn specialized in heavy metal poisoning. After she spilled a few drops of this compound on her latex glove, the barrier was compromised, and within minutes it was absorbed into her skin. It circulated through her body and accumulated in her brain, resulting in her death ten months later. This accident is a common toxicology case-study and directly resulted in improved safety procedures for chemical-protection clothing and fume use, which are now called for when any exposure to such severely toxic and/or highly penetrative substances is possible (e.g., in chemical munitions stockpiles and decontamination facilities).




    The beauty of it is that dimethylmercury is easily synthesized:




    The compound was one of the earliest organometallics reported, reflecting its considerable stability. It is formed by treating sodium amalgam with methyl halides:



    $mathrm{Hg} + 2 mathrm{Na} + 2 mathrm {CH}_3mathrm{I} rightarrow mathrm {Hg}(mathrm{CH}_3)_2 + 2 mathrm {NaI}$




    Methyl iodide ($mathrm {CH}_3mathrm{I}$) itself is also easy to make.



    All in all, all you need in order to make one the deadliest known substances is access to a high-school chemistry laboratory.







    share|improve this answer














    share|improve this answer



    share|improve this answer








    edited yesterday

























    answered yesterday









    AlexPAlexP

    41.8k894165




    41.8k894165












    • $begingroup$
      Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
      $endgroup$
      – WhatRoughBeast
      yesterday






    • 2




      $begingroup$
      @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
      $endgroup$
      – Ville Niemi
      yesterday


















    • $begingroup$
      Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
      $endgroup$
      – WhatRoughBeast
      yesterday






    • 2




      $begingroup$
      @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
      $endgroup$
      – Ville Niemi
      yesterday
















    $begingroup$
    Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
    $endgroup$
    – WhatRoughBeast
    yesterday




    $begingroup$
    Although it should be kept in mind that diethylmercury takes a LONG time to kill. The "canonical" victim, Karen Wetterhahn, took nearly a year. So, patience becomes a virtue in the story.
    $endgroup$
    – WhatRoughBeast
    yesterday




    2




    2




    $begingroup$
    @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
    $endgroup$
    – Ville Niemi
    yesterday




    $begingroup$
    @WhatRoughBeast Usually when you poison someone you want the death to lag enough that it becomes very hard to figure out where and when the victim got poisoned. So probably not a problem? I am more concerned of whether "access to a high-school chemistry lab" is good enough.
    $endgroup$
    – Ville Niemi
    yesterday











    12












    $begingroup$

    Honeybee.



    bee
    https://cronkitenews.azpbs.org/2018/02/21/advocacy-groups-pressure-state-to-ban-bee-killing-pesticides/



    I like this because if your victim is allergic, he can very definitely die from a bee sting. It takes seconds to get stung. This method is not applicable to the general population, so if user63214 is some disgruntled would-be murderer I am not an accessory. But for a story it could work just fine.






    share|improve this answer









    $endgroup$









    • 6




      $begingroup$
      I love the way your mind works.
      $endgroup$
      – JBH
      yesterday










    • $begingroup$
      Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
      $endgroup$
      – DarthDonut
      17 hours ago






    • 2




      $begingroup$
      @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
      $endgroup$
      – wizzwizz4
      16 hours ago


















    12












    $begingroup$

    Honeybee.



    bee
    https://cronkitenews.azpbs.org/2018/02/21/advocacy-groups-pressure-state-to-ban-bee-killing-pesticides/



    I like this because if your victim is allergic, he can very definitely die from a bee sting. It takes seconds to get stung. This method is not applicable to the general population, so if user63214 is some disgruntled would-be murderer I am not an accessory. But for a story it could work just fine.






    share|improve this answer









    $endgroup$









    • 6




      $begingroup$
      I love the way your mind works.
      $endgroup$
      – JBH
      yesterday










    • $begingroup$
      Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
      $endgroup$
      – DarthDonut
      17 hours ago






    • 2




      $begingroup$
      @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
      $endgroup$
      – wizzwizz4
      16 hours ago
















    12












    12








    12





    $begingroup$

    Honeybee.



    bee
    https://cronkitenews.azpbs.org/2018/02/21/advocacy-groups-pressure-state-to-ban-bee-killing-pesticides/



    I like this because if your victim is allergic, he can very definitely die from a bee sting. It takes seconds to get stung. This method is not applicable to the general population, so if user63214 is some disgruntled would-be murderer I am not an accessory. But for a story it could work just fine.






    share|improve this answer









    $endgroup$



    Honeybee.



    bee
    https://cronkitenews.azpbs.org/2018/02/21/advocacy-groups-pressure-state-to-ban-bee-killing-pesticides/



    I like this because if your victim is allergic, he can very definitely die from a bee sting. It takes seconds to get stung. This method is not applicable to the general population, so if user63214 is some disgruntled would-be murderer I am not an accessory. But for a story it could work just fine.







    share|improve this answer












    share|improve this answer



    share|improve this answer










    answered yesterday









    WillkWillk

    118k28222492




    118k28222492








    • 6




      $begingroup$
      I love the way your mind works.
      $endgroup$
      – JBH
      yesterday










    • $begingroup$
      Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
      $endgroup$
      – DarthDonut
      17 hours ago






    • 2




      $begingroup$
      @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
      $endgroup$
      – wizzwizz4
      16 hours ago
















    • 6




      $begingroup$
      I love the way your mind works.
      $endgroup$
      – JBH
      yesterday










    • $begingroup$
      Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
      $endgroup$
      – DarthDonut
      17 hours ago






    • 2




      $begingroup$
      @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
      $endgroup$
      – wizzwizz4
      16 hours ago










    6




    6




    $begingroup$
    I love the way your mind works.
    $endgroup$
    – JBH
    yesterday




    $begingroup$
    I love the way your mind works.
    $endgroup$
    – JBH
    yesterday












    $begingroup$
    Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
    $endgroup$
    – DarthDonut
    17 hours ago




    $begingroup$
    Most modern honeybees will not sting randomly, but only if they feel threatened. Maybe use wasps, these are some nasty little buggers.
    $endgroup$
    – DarthDonut
    17 hours ago




    2




    2




    $begingroup$
    @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
    $endgroup$
    – wizzwizz4
    16 hours ago






    $begingroup$
    @DarthDonut Snip off its antennas, or attach string to them. That'll make it perpetually feel threatened: there's always something touching its antennas; otherwise, why would they vibrate so strangely?
    $endgroup$
    – wizzwizz4
    16 hours ago













    6












    $begingroup$


    • Caffeine


      • known to work with DMSO (some people consume it this way)

      • wikipedia: "pure powdered caffeine, which is available as a dietary supplement, can be lethal in tablespoon-sized amounts"



    • Warfarin


      • accessible as rat poison

      • a few grams should be enough (1-5 mg tablets are used in medicine)

      • use with DMSO? no idea if that would work

      • causes bleeding, necrosis...



    • Hydrofluoric acid


      • indirectly accessible in glass etching kits

      • or you can just buy it

      • how scary do you wish your novel to be?








    share|improve this answer









    $endgroup$









    • 1




      $begingroup$
      " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
      $endgroup$
      – FooBar
      15 hours ago
















    6












    $begingroup$


    • Caffeine


      • known to work with DMSO (some people consume it this way)

      • wikipedia: "pure powdered caffeine, which is available as a dietary supplement, can be lethal in tablespoon-sized amounts"



    • Warfarin


      • accessible as rat poison

      • a few grams should be enough (1-5 mg tablets are used in medicine)

      • use with DMSO? no idea if that would work

      • causes bleeding, necrosis...



    • Hydrofluoric acid


      • indirectly accessible in glass etching kits

      • or you can just buy it

      • how scary do you wish your novel to be?








    share|improve this answer









    $endgroup$









    • 1




      $begingroup$
      " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
      $endgroup$
      – FooBar
      15 hours ago














    6












    6








    6





    $begingroup$


    • Caffeine


      • known to work with DMSO (some people consume it this way)

      • wikipedia: "pure powdered caffeine, which is available as a dietary supplement, can be lethal in tablespoon-sized amounts"



    • Warfarin


      • accessible as rat poison

      • a few grams should be enough (1-5 mg tablets are used in medicine)

      • use with DMSO? no idea if that would work

      • causes bleeding, necrosis...



    • Hydrofluoric acid


      • indirectly accessible in glass etching kits

      • or you can just buy it

      • how scary do you wish your novel to be?








    share|improve this answer









    $endgroup$




    • Caffeine


      • known to work with DMSO (some people consume it this way)

      • wikipedia: "pure powdered caffeine, which is available as a dietary supplement, can be lethal in tablespoon-sized amounts"



    • Warfarin


      • accessible as rat poison

      • a few grams should be enough (1-5 mg tablets are used in medicine)

      • use with DMSO? no idea if that would work

      • causes bleeding, necrosis...



    • Hydrofluoric acid


      • indirectly accessible in glass etching kits

      • or you can just buy it

      • how scary do you wish your novel to be?









    share|improve this answer












    share|improve this answer



    share|improve this answer










    answered yesterday









    jakub_djakub_d

    1991




    1991








    • 1




      $begingroup$
      " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
      $endgroup$
      – FooBar
      15 hours ago














    • 1




      $begingroup$
      " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
      $endgroup$
      – FooBar
      15 hours ago








    1




    1




    $begingroup$
    " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
    $endgroup$
    – FooBar
    15 hours ago




    $begingroup$
    " tablespoon-sized amounts" if you eat it, not if you hold it in your hand
    $endgroup$
    – FooBar
    15 hours ago











    6












    $begingroup$

    Ricin



    See here and here.



    Made from the castor bean, the plant can be found as a common ornamental in parks and gardens.



    There is no antidote.



    @AlexP also provides a great vector.



    I am not going in to production and delivery but no special requirements and a little creative thought should show how this could be achieved.






    share|improve this answer









    $endgroup$













    • $begingroup$
      The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
      $endgroup$
      – Stormbolter
      15 hours ago










    • $begingroup$
      Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
      $endgroup$
      – pHred
      4 hours ago
















    6












    $begingroup$

    Ricin



    See here and here.



    Made from the castor bean, the plant can be found as a common ornamental in parks and gardens.



    There is no antidote.



    @AlexP also provides a great vector.



    I am not going in to production and delivery but no special requirements and a little creative thought should show how this could be achieved.






    share|improve this answer









    $endgroup$













    • $begingroup$
      The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
      $endgroup$
      – Stormbolter
      15 hours ago










    • $begingroup$
      Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
      $endgroup$
      – pHred
      4 hours ago














    6












    6








    6





    $begingroup$

    Ricin



    See here and here.



    Made from the castor bean, the plant can be found as a common ornamental in parks and gardens.



    There is no antidote.



    @AlexP also provides a great vector.



    I am not going in to production and delivery but no special requirements and a little creative thought should show how this could be achieved.






    share|improve this answer









    $endgroup$



    Ricin



    See here and here.



    Made from the castor bean, the plant can be found as a common ornamental in parks and gardens.



    There is no antidote.



    @AlexP also provides a great vector.



    I am not going in to production and delivery but no special requirements and a little creative thought should show how this could be achieved.







    share|improve this answer












    share|improve this answer



    share|improve this answer










    answered yesterday









    pHredpHred

    1,471610




    1,471610












    • $begingroup$
      The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
      $endgroup$
      – Stormbolter
      15 hours ago










    • $begingroup$
      Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
      $endgroup$
      – pHred
      4 hours ago


















    • $begingroup$
      The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
      $endgroup$
      – Stormbolter
      15 hours ago










    • $begingroup$
      Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
      $endgroup$
      – pHred
      4 hours ago
















    $begingroup$
    The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
    $endgroup$
    – Stormbolter
    15 hours ago




    $begingroup$
    The problem with ricin is that it needs to be injected on the bloodstream to be effective. So delivery upon holding an item would be hard to disguise.
    $endgroup$
    – Stormbolter
    15 hours ago












    $begingroup$
    Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
    $endgroup$
    – pHred
    4 hours ago




    $begingroup$
    Not necessarily. See the skin and ingestion routes in the second reference. Granted it is most effective when introduced directly into tissue but consider what would occur if someone had a cut or abrasion. Also consider DMSO as a carrier.
    $endgroup$
    – pHred
    4 hours ago











    1












    $begingroup$

    Here's another accessible chemical compound that hasn't been mentioned so far:



    Dimethyl sulfate




    Like all strong alkylating agents, $(text{CH}_3text{O})_2text{SO}_2$ or $text{Me}_2text{SO}_4$ is extremely toxic. Its use as a laboratory reagent has been superseded to some extent by methyl triflate, the methyl ester of trifluoromethanesulfonic acid.




    It can be synthesized in the laboratory by many different methods, the simplest being the esterification of sulfuric acid with methanol. Another possible synthesis involves distillation of methyl hydrogen sulfate.




    Dimethyl sulfate is carcinogenic and mutagenic, highly poisonous, corrosive, and environmentally hazardous. Dimethyl sulfate is absorbed through the skin, mucous membranes, and gastrointestinal tract, and can cause a fatal delayed respiratory tract reaction. An ocular reaction is also common. There is no strong odor or immediate irritation to warn of lethal concentration in the air.







    share|improve this answer








    New contributor




    polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
    Check out our Code of Conduct.






    $endgroup$


















      1












      $begingroup$

      Here's another accessible chemical compound that hasn't been mentioned so far:



      Dimethyl sulfate




      Like all strong alkylating agents, $(text{CH}_3text{O})_2text{SO}_2$ or $text{Me}_2text{SO}_4$ is extremely toxic. Its use as a laboratory reagent has been superseded to some extent by methyl triflate, the methyl ester of trifluoromethanesulfonic acid.




      It can be synthesized in the laboratory by many different methods, the simplest being the esterification of sulfuric acid with methanol. Another possible synthesis involves distillation of methyl hydrogen sulfate.




      Dimethyl sulfate is carcinogenic and mutagenic, highly poisonous, corrosive, and environmentally hazardous. Dimethyl sulfate is absorbed through the skin, mucous membranes, and gastrointestinal tract, and can cause a fatal delayed respiratory tract reaction. An ocular reaction is also common. There is no strong odor or immediate irritation to warn of lethal concentration in the air.







      share|improve this answer








      New contributor




      polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
      Check out our Code of Conduct.






      $endgroup$
















        1












        1








        1





        $begingroup$

        Here's another accessible chemical compound that hasn't been mentioned so far:



        Dimethyl sulfate




        Like all strong alkylating agents, $(text{CH}_3text{O})_2text{SO}_2$ or $text{Me}_2text{SO}_4$ is extremely toxic. Its use as a laboratory reagent has been superseded to some extent by methyl triflate, the methyl ester of trifluoromethanesulfonic acid.




        It can be synthesized in the laboratory by many different methods, the simplest being the esterification of sulfuric acid with methanol. Another possible synthesis involves distillation of methyl hydrogen sulfate.




        Dimethyl sulfate is carcinogenic and mutagenic, highly poisonous, corrosive, and environmentally hazardous. Dimethyl sulfate is absorbed through the skin, mucous membranes, and gastrointestinal tract, and can cause a fatal delayed respiratory tract reaction. An ocular reaction is also common. There is no strong odor or immediate irritation to warn of lethal concentration in the air.







        share|improve this answer








        New contributor




        polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.






        $endgroup$



        Here's another accessible chemical compound that hasn't been mentioned so far:



        Dimethyl sulfate




        Like all strong alkylating agents, $(text{CH}_3text{O})_2text{SO}_2$ or $text{Me}_2text{SO}_4$ is extremely toxic. Its use as a laboratory reagent has been superseded to some extent by methyl triflate, the methyl ester of trifluoromethanesulfonic acid.




        It can be synthesized in the laboratory by many different methods, the simplest being the esterification of sulfuric acid with methanol. Another possible synthesis involves distillation of methyl hydrogen sulfate.




        Dimethyl sulfate is carcinogenic and mutagenic, highly poisonous, corrosive, and environmentally hazardous. Dimethyl sulfate is absorbed through the skin, mucous membranes, and gastrointestinal tract, and can cause a fatal delayed respiratory tract reaction. An ocular reaction is also common. There is no strong odor or immediate irritation to warn of lethal concentration in the air.








        share|improve this answer








        New contributor




        polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.









        share|improve this answer



        share|improve this answer






        New contributor




        polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.









        answered 15 hours ago









        polfosolpolfosol

        1135




        1135




        New contributor




        polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.





        New contributor





        polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.






        polfosol is a new contributor to this site. Take care in asking for clarification, commenting, and answering.
        Check out our Code of Conduct.























            0












            $begingroup$

            While i do not know of any easily obtained chemicals or substances that can kill as you just through contact of your palm (probably a good thing for the general population) i can offer you some ideas.



            Delivery



            Firstly though, i am going to present you with a possible delivery system. As many chemicals need to be in your bloodstream to take effect, we would need some way of transferring them there. Thusly, i present you with The Assassin’s Glove (name pending).



            This would be a glove who’s palm is laced with hypodermic needles, similar to those you may find in nettles. As you shook someone’s hand, these needles would be pressed against their palm and inject the substance into their body. With this glove, you could inject practically anything into the target. Here are some suggestions:



            Substances



            Snake venom is relatively easy to obtain, assuming you can find and extract the venom from one. However, as it is a venom, it can’t kill you unless it enters your blood stream. You can safely drink snake venom if you do not have any cuts from your mouth to your stomach. However, if you had a cut or it was injected into you, then you would feel its effects.



            Cyanide is a classic killer, you can extract it from apple seeds if your protagonist truly has no access to any kind of harmful substance.



            Hydrochloric acid, extracted from bleach, may also do the job. Bleach does have a strong smell to it though which may give your assassin away.



            Alternatively



            If you’re just looking for a way to stealthily kill someone, polonium has famously been used. It is a radioactive substance which emits alpha radiation. Alpha radiation can not penetrate human skin but, of ingested, it is fatal. The reason it kills you is the same reason you are normally safe from it, it can’t penetrate your skin, meaning its stuck inside you and damages your DNA. It would likely take weeks or months to kill someone this way but it has been used in the past. You might also be able to inject it to get a similar effect.






            share|improve this answer









            $endgroup$









            • 1




              $begingroup$
              Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              Contaminating the toothbrush is way more creative than the assassin's glove.
              $endgroup$
              – polfosol
              16 hours ago
















            0












            $begingroup$

            While i do not know of any easily obtained chemicals or substances that can kill as you just through contact of your palm (probably a good thing for the general population) i can offer you some ideas.



            Delivery



            Firstly though, i am going to present you with a possible delivery system. As many chemicals need to be in your bloodstream to take effect, we would need some way of transferring them there. Thusly, i present you with The Assassin’s Glove (name pending).



            This would be a glove who’s palm is laced with hypodermic needles, similar to those you may find in nettles. As you shook someone’s hand, these needles would be pressed against their palm and inject the substance into their body. With this glove, you could inject practically anything into the target. Here are some suggestions:



            Substances



            Snake venom is relatively easy to obtain, assuming you can find and extract the venom from one. However, as it is a venom, it can’t kill you unless it enters your blood stream. You can safely drink snake venom if you do not have any cuts from your mouth to your stomach. However, if you had a cut or it was injected into you, then you would feel its effects.



            Cyanide is a classic killer, you can extract it from apple seeds if your protagonist truly has no access to any kind of harmful substance.



            Hydrochloric acid, extracted from bleach, may also do the job. Bleach does have a strong smell to it though which may give your assassin away.



            Alternatively



            If you’re just looking for a way to stealthily kill someone, polonium has famously been used. It is a radioactive substance which emits alpha radiation. Alpha radiation can not penetrate human skin but, of ingested, it is fatal. The reason it kills you is the same reason you are normally safe from it, it can’t penetrate your skin, meaning its stuck inside you and damages your DNA. It would likely take weeks or months to kill someone this way but it has been used in the past. You might also be able to inject it to get a similar effect.






            share|improve this answer









            $endgroup$









            • 1




              $begingroup$
              Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              Contaminating the toothbrush is way more creative than the assassin's glove.
              $endgroup$
              – polfosol
              16 hours ago














            0












            0








            0





            $begingroup$

            While i do not know of any easily obtained chemicals or substances that can kill as you just through contact of your palm (probably a good thing for the general population) i can offer you some ideas.



            Delivery



            Firstly though, i am going to present you with a possible delivery system. As many chemicals need to be in your bloodstream to take effect, we would need some way of transferring them there. Thusly, i present you with The Assassin’s Glove (name pending).



            This would be a glove who’s palm is laced with hypodermic needles, similar to those you may find in nettles. As you shook someone’s hand, these needles would be pressed against their palm and inject the substance into their body. With this glove, you could inject practically anything into the target. Here are some suggestions:



            Substances



            Snake venom is relatively easy to obtain, assuming you can find and extract the venom from one. However, as it is a venom, it can’t kill you unless it enters your blood stream. You can safely drink snake venom if you do not have any cuts from your mouth to your stomach. However, if you had a cut or it was injected into you, then you would feel its effects.



            Cyanide is a classic killer, you can extract it from apple seeds if your protagonist truly has no access to any kind of harmful substance.



            Hydrochloric acid, extracted from bleach, may also do the job. Bleach does have a strong smell to it though which may give your assassin away.



            Alternatively



            If you’re just looking for a way to stealthily kill someone, polonium has famously been used. It is a radioactive substance which emits alpha radiation. Alpha radiation can not penetrate human skin but, of ingested, it is fatal. The reason it kills you is the same reason you are normally safe from it, it can’t penetrate your skin, meaning its stuck inside you and damages your DNA. It would likely take weeks or months to kill someone this way but it has been used in the past. You might also be able to inject it to get a similar effect.






            share|improve this answer









            $endgroup$



            While i do not know of any easily obtained chemicals or substances that can kill as you just through contact of your palm (probably a good thing for the general population) i can offer you some ideas.



            Delivery



            Firstly though, i am going to present you with a possible delivery system. As many chemicals need to be in your bloodstream to take effect, we would need some way of transferring them there. Thusly, i present you with The Assassin’s Glove (name pending).



            This would be a glove who’s palm is laced with hypodermic needles, similar to those you may find in nettles. As you shook someone’s hand, these needles would be pressed against their palm and inject the substance into their body. With this glove, you could inject practically anything into the target. Here are some suggestions:



            Substances



            Snake venom is relatively easy to obtain, assuming you can find and extract the venom from one. However, as it is a venom, it can’t kill you unless it enters your blood stream. You can safely drink snake venom if you do not have any cuts from your mouth to your stomach. However, if you had a cut or it was injected into you, then you would feel its effects.



            Cyanide is a classic killer, you can extract it from apple seeds if your protagonist truly has no access to any kind of harmful substance.



            Hydrochloric acid, extracted from bleach, may also do the job. Bleach does have a strong smell to it though which may give your assassin away.



            Alternatively



            If you’re just looking for a way to stealthily kill someone, polonium has famously been used. It is a radioactive substance which emits alpha radiation. Alpha radiation can not penetrate human skin but, of ingested, it is fatal. The reason it kills you is the same reason you are normally safe from it, it can’t penetrate your skin, meaning its stuck inside you and damages your DNA. It would likely take weeks or months to kill someone this way but it has been used in the past. You might also be able to inject it to get a similar effect.







            share|improve this answer












            share|improve this answer



            share|improve this answer










            answered yesterday









            Liam MorrisLiam Morris

            2,242430




            2,242430








            • 1




              $begingroup$
              Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              Contaminating the toothbrush is way more creative than the assassin's glove.
              $endgroup$
              – polfosol
              16 hours ago














            • 1




              $begingroup$
              Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              Contaminating the toothbrush is way more creative than the assassin's glove.
              $endgroup$
              – polfosol
              16 hours ago








            1




            1




            $begingroup$
            Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
            $endgroup$
            – jwenting
            19 hours ago




            $begingroup$
            Shaking hands while gloved is not something you do in polite society. But brushing the gloved hand along someone's arm or face would do the same and be made to look like an accidental touch.
            $endgroup$
            – jwenting
            19 hours ago












            $begingroup$
            Contaminating the toothbrush is way more creative than the assassin's glove.
            $endgroup$
            – polfosol
            16 hours ago




            $begingroup$
            Contaminating the toothbrush is way more creative than the assassin's glove.
            $endgroup$
            – polfosol
            16 hours ago











            -1












            $begingroup$

            Elemental Mercury



            Okay, this doesn't really meet your requirements. Not much is absorbed through the skin. But mercury in your hand is fun to play with and your victim might keep it on longer than 4-5 seconds. The danger is from the vapors. If your plot allows, pouring large amounts of mercury around the victim's bed or car, or another relatively small space where the victim spends a lot of time, might do the trick.



            Elemental mercury is what's in thermometers (the kind without batteries), so it would be relatively simple (though expensive and time consuming) to gather enough for the perpetrator to use (assuming a lot of safety equipment, the kind easily found online). The more dangerous form of mercury is methyl mercury, but that's not exactly sold in handy dandy glass containers. Mercury also has medical applications but purchasing it in larger quantities might prove more difficult.



            Instead of buying old fashioned thermometers, the perp might want to buy new digital ones and offer them free to doctor's clinics and households and schools in exchange for mercury ones (as a way to reduce potential toxic exposures...swap programs like this probably already exist legitimately). You may also have some luck with fluorescent light bulbs.




            Elemental mercury, also called “quicksilver,” is a heavy, silvery,
            form of the metal mercury that is liquid at room temperature. It can
            slowly change from a liquid into a gas that is invisible to the naked
            eye. The gas or “vapors” that are released will start to fill a room
            if mercury is spilled indoors.



            Mercury is a very
            toxic or poisonous substance that people can be exposed to in several
            ways. If it is swallowed, like from a broken thermometer, it mostly
            passes through your body and very little is absorbed. If you touch it,
            a small amount may pass through your skin, but not usually enough to
            harm you. Mercury is most harmful when you breathe in the vapors that
            are released when a container is open or a spill occurs. (ref)




            Will elemental mercury fumes kill a victim? Maybe. But organ damage (which you allow as an alternative) is more likely.




            How much mercury spilled in a room will make air in the room unsafe?
            Any amount of mercury spilled indoors can be hazardous. The more
            mercury is spilled, the more its vapor will build up in air and the
            more hazardous it will be. Even a small spill, such as from a broken
            thermometer, can produce hazardous amounts of vapor if a room is small
            enough, warm enough and people spend a good deal of time there, as in
            a small bedroom.
            (ref)




            Spilling the mercury on to a hot surface (like a stove) will vaporize it quickly. Spilling it elsewhere will allow the vapors to accumulate more slowly. The liquid form is easily tracked through a house and hard to get rid of.




            Inhalation of elemental mercury vapors is the main source of toxicity,
            as mercury is well-absorbed through the lungs. Problems from
            inhalation result either from a large one-time high exposure or a
            long-term exposure. Long-term exposure of inhaled vapors is generally
            more dangerous, with the nervous system being the primary target of
            mercury toxicity. Symptoms may occur within weeks but usually develop
            insidiously over a period of years. Neurologic symptoms include
            tremors, headaches, short-term memory loss, incoordination, weakness,
            loss of appetite, altered sense of taste and smell, numbness and
            tingling in the hands and feet, insomnia, and excessive sweating.
            Psychiatric effects are also seen after long-term exposure. The
            kidneys can also be effected. Intense exposure to high concentrations
            of mercury vapor can lead to severe respiratory damage
            . (ref)




            So there you have it. Organ damage from even short-term exposures. But not from being held in the hand. Consider that a frame challenge, that the substance you are imagining probably does not exist. But you can combine mercury in the hand with mercury spilling all over the place and creating fumes. Maybe try when the victim is locked into a sauna for an hour. There are many possibilities.






            share|improve this answer











            $endgroup$









            • 3




              $begingroup$
              Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
              $endgroup$
              – AlexP
              yesterday












            • $begingroup$
              @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
              $endgroup$
              – Cyn
              16 hours ago
















            -1












            $begingroup$

            Elemental Mercury



            Okay, this doesn't really meet your requirements. Not much is absorbed through the skin. But mercury in your hand is fun to play with and your victim might keep it on longer than 4-5 seconds. The danger is from the vapors. If your plot allows, pouring large amounts of mercury around the victim's bed or car, or another relatively small space where the victim spends a lot of time, might do the trick.



            Elemental mercury is what's in thermometers (the kind without batteries), so it would be relatively simple (though expensive and time consuming) to gather enough for the perpetrator to use (assuming a lot of safety equipment, the kind easily found online). The more dangerous form of mercury is methyl mercury, but that's not exactly sold in handy dandy glass containers. Mercury also has medical applications but purchasing it in larger quantities might prove more difficult.



            Instead of buying old fashioned thermometers, the perp might want to buy new digital ones and offer them free to doctor's clinics and households and schools in exchange for mercury ones (as a way to reduce potential toxic exposures...swap programs like this probably already exist legitimately). You may also have some luck with fluorescent light bulbs.




            Elemental mercury, also called “quicksilver,” is a heavy, silvery,
            form of the metal mercury that is liquid at room temperature. It can
            slowly change from a liquid into a gas that is invisible to the naked
            eye. The gas or “vapors” that are released will start to fill a room
            if mercury is spilled indoors.



            Mercury is a very
            toxic or poisonous substance that people can be exposed to in several
            ways. If it is swallowed, like from a broken thermometer, it mostly
            passes through your body and very little is absorbed. If you touch it,
            a small amount may pass through your skin, but not usually enough to
            harm you. Mercury is most harmful when you breathe in the vapors that
            are released when a container is open or a spill occurs. (ref)




            Will elemental mercury fumes kill a victim? Maybe. But organ damage (which you allow as an alternative) is more likely.




            How much mercury spilled in a room will make air in the room unsafe?
            Any amount of mercury spilled indoors can be hazardous. The more
            mercury is spilled, the more its vapor will build up in air and the
            more hazardous it will be. Even a small spill, such as from a broken
            thermometer, can produce hazardous amounts of vapor if a room is small
            enough, warm enough and people spend a good deal of time there, as in
            a small bedroom.
            (ref)




            Spilling the mercury on to a hot surface (like a stove) will vaporize it quickly. Spilling it elsewhere will allow the vapors to accumulate more slowly. The liquid form is easily tracked through a house and hard to get rid of.




            Inhalation of elemental mercury vapors is the main source of toxicity,
            as mercury is well-absorbed through the lungs. Problems from
            inhalation result either from a large one-time high exposure or a
            long-term exposure. Long-term exposure of inhaled vapors is generally
            more dangerous, with the nervous system being the primary target of
            mercury toxicity. Symptoms may occur within weeks but usually develop
            insidiously over a period of years. Neurologic symptoms include
            tremors, headaches, short-term memory loss, incoordination, weakness,
            loss of appetite, altered sense of taste and smell, numbness and
            tingling in the hands and feet, insomnia, and excessive sweating.
            Psychiatric effects are also seen after long-term exposure. The
            kidneys can also be effected. Intense exposure to high concentrations
            of mercury vapor can lead to severe respiratory damage
            . (ref)




            So there you have it. Organ damage from even short-term exposures. But not from being held in the hand. Consider that a frame challenge, that the substance you are imagining probably does not exist. But you can combine mercury in the hand with mercury spilling all over the place and creating fumes. Maybe try when the victim is locked into a sauna for an hour. There are many possibilities.






            share|improve this answer











            $endgroup$









            • 3




              $begingroup$
              Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
              $endgroup$
              – AlexP
              yesterday












            • $begingroup$
              @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
              $endgroup$
              – Cyn
              16 hours ago














            -1












            -1








            -1





            $begingroup$

            Elemental Mercury



            Okay, this doesn't really meet your requirements. Not much is absorbed through the skin. But mercury in your hand is fun to play with and your victim might keep it on longer than 4-5 seconds. The danger is from the vapors. If your plot allows, pouring large amounts of mercury around the victim's bed or car, or another relatively small space where the victim spends a lot of time, might do the trick.



            Elemental mercury is what's in thermometers (the kind without batteries), so it would be relatively simple (though expensive and time consuming) to gather enough for the perpetrator to use (assuming a lot of safety equipment, the kind easily found online). The more dangerous form of mercury is methyl mercury, but that's not exactly sold in handy dandy glass containers. Mercury also has medical applications but purchasing it in larger quantities might prove more difficult.



            Instead of buying old fashioned thermometers, the perp might want to buy new digital ones and offer them free to doctor's clinics and households and schools in exchange for mercury ones (as a way to reduce potential toxic exposures...swap programs like this probably already exist legitimately). You may also have some luck with fluorescent light bulbs.




            Elemental mercury, also called “quicksilver,” is a heavy, silvery,
            form of the metal mercury that is liquid at room temperature. It can
            slowly change from a liquid into a gas that is invisible to the naked
            eye. The gas or “vapors” that are released will start to fill a room
            if mercury is spilled indoors.



            Mercury is a very
            toxic or poisonous substance that people can be exposed to in several
            ways. If it is swallowed, like from a broken thermometer, it mostly
            passes through your body and very little is absorbed. If you touch it,
            a small amount may pass through your skin, but not usually enough to
            harm you. Mercury is most harmful when you breathe in the vapors that
            are released when a container is open or a spill occurs. (ref)




            Will elemental mercury fumes kill a victim? Maybe. But organ damage (which you allow as an alternative) is more likely.




            How much mercury spilled in a room will make air in the room unsafe?
            Any amount of mercury spilled indoors can be hazardous. The more
            mercury is spilled, the more its vapor will build up in air and the
            more hazardous it will be. Even a small spill, such as from a broken
            thermometer, can produce hazardous amounts of vapor if a room is small
            enough, warm enough and people spend a good deal of time there, as in
            a small bedroom.
            (ref)




            Spilling the mercury on to a hot surface (like a stove) will vaporize it quickly. Spilling it elsewhere will allow the vapors to accumulate more slowly. The liquid form is easily tracked through a house and hard to get rid of.




            Inhalation of elemental mercury vapors is the main source of toxicity,
            as mercury is well-absorbed through the lungs. Problems from
            inhalation result either from a large one-time high exposure or a
            long-term exposure. Long-term exposure of inhaled vapors is generally
            more dangerous, with the nervous system being the primary target of
            mercury toxicity. Symptoms may occur within weeks but usually develop
            insidiously over a period of years. Neurologic symptoms include
            tremors, headaches, short-term memory loss, incoordination, weakness,
            loss of appetite, altered sense of taste and smell, numbness and
            tingling in the hands and feet, insomnia, and excessive sweating.
            Psychiatric effects are also seen after long-term exposure. The
            kidneys can also be effected. Intense exposure to high concentrations
            of mercury vapor can lead to severe respiratory damage
            . (ref)




            So there you have it. Organ damage from even short-term exposures. But not from being held in the hand. Consider that a frame challenge, that the substance you are imagining probably does not exist. But you can combine mercury in the hand with mercury spilling all over the place and creating fumes. Maybe try when the victim is locked into a sauna for an hour. There are many possibilities.






            share|improve this answer











            $endgroup$



            Elemental Mercury



            Okay, this doesn't really meet your requirements. Not much is absorbed through the skin. But mercury in your hand is fun to play with and your victim might keep it on longer than 4-5 seconds. The danger is from the vapors. If your plot allows, pouring large amounts of mercury around the victim's bed or car, or another relatively small space where the victim spends a lot of time, might do the trick.



            Elemental mercury is what's in thermometers (the kind without batteries), so it would be relatively simple (though expensive and time consuming) to gather enough for the perpetrator to use (assuming a lot of safety equipment, the kind easily found online). The more dangerous form of mercury is methyl mercury, but that's not exactly sold in handy dandy glass containers. Mercury also has medical applications but purchasing it in larger quantities might prove more difficult.



            Instead of buying old fashioned thermometers, the perp might want to buy new digital ones and offer them free to doctor's clinics and households and schools in exchange for mercury ones (as a way to reduce potential toxic exposures...swap programs like this probably already exist legitimately). You may also have some luck with fluorescent light bulbs.




            Elemental mercury, also called “quicksilver,” is a heavy, silvery,
            form of the metal mercury that is liquid at room temperature. It can
            slowly change from a liquid into a gas that is invisible to the naked
            eye. The gas or “vapors” that are released will start to fill a room
            if mercury is spilled indoors.



            Mercury is a very
            toxic or poisonous substance that people can be exposed to in several
            ways. If it is swallowed, like from a broken thermometer, it mostly
            passes through your body and very little is absorbed. If you touch it,
            a small amount may pass through your skin, but not usually enough to
            harm you. Mercury is most harmful when you breathe in the vapors that
            are released when a container is open or a spill occurs. (ref)




            Will elemental mercury fumes kill a victim? Maybe. But organ damage (which you allow as an alternative) is more likely.




            How much mercury spilled in a room will make air in the room unsafe?
            Any amount of mercury spilled indoors can be hazardous. The more
            mercury is spilled, the more its vapor will build up in air and the
            more hazardous it will be. Even a small spill, such as from a broken
            thermometer, can produce hazardous amounts of vapor if a room is small
            enough, warm enough and people spend a good deal of time there, as in
            a small bedroom.
            (ref)




            Spilling the mercury on to a hot surface (like a stove) will vaporize it quickly. Spilling it elsewhere will allow the vapors to accumulate more slowly. The liquid form is easily tracked through a house and hard to get rid of.




            Inhalation of elemental mercury vapors is the main source of toxicity,
            as mercury is well-absorbed through the lungs. Problems from
            inhalation result either from a large one-time high exposure or a
            long-term exposure. Long-term exposure of inhaled vapors is generally
            more dangerous, with the nervous system being the primary target of
            mercury toxicity. Symptoms may occur within weeks but usually develop
            insidiously over a period of years. Neurologic symptoms include
            tremors, headaches, short-term memory loss, incoordination, weakness,
            loss of appetite, altered sense of taste and smell, numbness and
            tingling in the hands and feet, insomnia, and excessive sweating.
            Psychiatric effects are also seen after long-term exposure. The
            kidneys can also be effected. Intense exposure to high concentrations
            of mercury vapor can lead to severe respiratory damage
            . (ref)




            So there you have it. Organ damage from even short-term exposures. But not from being held in the hand. Consider that a frame challenge, that the substance you are imagining probably does not exist. But you can combine mercury in the hand with mercury spilling all over the place and creating fumes. Maybe try when the victim is locked into a sauna for an hour. There are many possibilities.







            share|improve this answer














            share|improve this answer



            share|improve this answer








            edited yesterday

























            answered yesterday









            CynCyn

            11.7k12458




            11.7k12458








            • 3




              $begingroup$
              Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
              $endgroup$
              – AlexP
              yesterday












            • $begingroup$
              @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
              $endgroup$
              – Cyn
              16 hours ago














            • 3




              $begingroup$
              Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
              $endgroup$
              – AlexP
              yesterday












            • $begingroup$
              @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
              $endgroup$
              – Cyn
              yesterday










            • $begingroup$
              @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
              $endgroup$
              – jwenting
              19 hours ago










            • $begingroup$
              @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
              $endgroup$
              – Cyn
              16 hours ago








            3




            3




            $begingroup$
            Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
            $endgroup$
            – AlexP
            yesterday






            $begingroup$
            Metallic mercury is not really all that dangerous. You can play with it, hold it in your hand, just don't eat it and don't overdo it. The danger comes from chronic exposure to mercury vapor. After all, it was used for thousands of years and it did not cause massive mortality... People of a certain age still remember when mercurcy thermometers were readily availale.
            $endgroup$
            – AlexP
            yesterday














            $begingroup$
            @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
            $endgroup$
            – Cyn
            yesterday




            $begingroup$
            @AlexP it's dangerous enough. The links I provided talk about how mercury vapor in heat and a small enclosed space can cause damage. And what if you breathed the vapors from 500 mercury thermometers? I am of a certain age and actually had a thermometer break (the metal cap came off) in my mouth. A year or two later my doctor was alarmed to see that it was enough to raise my mercury levels in my body to a significant level (not super high but definitely not in the normal range). I had immediately rinsed out my mouth too; I didn't swallow it.
            $endgroup$
            – Cyn
            yesterday












            $begingroup$
            There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
            $endgroup$
            – Cyn
            yesterday




            $begingroup$
            There is very very little mercury in a thermometer. I'm not talking about using one. Think hundreds. Or even over 1000 thermometer's worth of liquid around the room. Yes, one big exposure can do it. Though chronic exposure for sure is generally worse.
            $endgroup$
            – Cyn
            yesterday












            $begingroup$
            @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
            $endgroup$
            – jwenting
            19 hours ago




            $begingroup$
            @Cyn the amount of mercury needed to attain a lethal dose of mercury poisoning in one single exposure is far greater than what OP probably wants to use in his plot.
            $endgroup$
            – jwenting
            19 hours ago












            $begingroup$
            @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
            $endgroup$
            – Cyn
            16 hours ago




            $begingroup$
            @jwenting A lethal dose is not part of the requirements. The OP specified that organ damage was good enough. My links show this is possible.
            $endgroup$
            – Cyn
            16 hours ago










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